Within Campaign Sidekick, you can create large, unrouted lists of over 50 houses or small, computer-routed lists of 50 or less. Most campaigns will use both types of lists with frequency.
This video walks you through creation of large walklists.
Large lists are ideal for super-canvassers, teams of walkers and voter-dense turf. Cutting large lists also negates the need to have the computer optimize your walk path.
Small walklists work very well for individual walkers, printed/offline canvassing, volunteers who don't knock many doors and walk areas that require frequent driving. Once created, small lists must be route-optimized before being available for assignment to canvassers.